Chemical and Biomolecular Engineering

Top 20 Doctoral Program — National Research Council

Faculty

Mehmet Orman
Dr. Mehmet Orman

Assistant Professor of Chemical and Biomolecular Engineering

Phone: 713-743-6785   |   Fax: 713-743-4323
Email: morman [at] central [dot] uh [dot] edu

Education: 

Ph.D., Chemical & Biochemical Engineering, Rutgers University, 2011
M.S., Chemical Engineering, METU, Turkey, 2007
B.S., Chemical Engineering Department, METU, Turkey, 2005

Journal Papers / Refereed Journal Publications

  1. Orman MA, Brynildsen MP,

    Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide, Free Radical Biology and Medicine, 93:145-154

    , 2016
  2. Orman MA, Henry TC, DeCoste CJ, Brynildsen MP,

    Analyzing persister physiology with fluorescence activated cell sorting, Methods in Molecular Biology, 1333: 83-100

    , 2016
  3. Rao RT, Yang Q, Orman MA, Berthiaume F, Ierapetritou MG, Androulakis IP,

    Burn trauma disrupts circadian rhythms in rat livers, International Journal of Burns and Trauma, 6:12

    , 2016
  4. Mok WWK*, Orman MA*, Brynildsen MP,

    Impacts of Global Regulators on Persistence Metabolism, Antimicrobial Agents and Chemotherapy, 59(5):2713-2719. *Contributed equally

    , 2015
  5. Orman MA, Brynildsen MP,

    Inhibition of Stationary Phase Metabolism Prevents Self-digestion and Persister Formation in E. coli, Nature Communications, 6:7983

    , 2015
  6. Orman MA, Mok WWK, Brynildsen MP,

    Aminoglycoside-enabled Elucidation of Bacterial Persister Metabolism, Current Protocols in Microbiology, 36:17.9.1-17.9.14

    , 2015
  7. Rao RT, Orman MA, Berthiaume F, Androulakis IP,

    Dynamics of Hepatic Gene Expression and Serum Cytokine Profiles in Single and Double-hit Burn and Sepsis Animal Models, Data in Brief, 3: 229-233

    , 2015
  8. Amato SM*, Fazen CH*, Henry T*, Mok WWK*, Orman MA*, Sandvik EL*, Volzing KG*, Brynildsen MP,

    The role of metabolism in bacterial persistence, Frontiers in Microbiology, 5:70. *Contributed equally

    , 2014
  9. Nyugen TT, Yang Q, Mattick J, Orman MA, Ierapetritou MG, Berthiaume F, Androulakis IP,

    Bioinformatic analysis of transcriptional regulation of circadian- relevant genes in rat liver, BMC Bioinformatics, 15:83

    , 2014
  10. Amato S, Orman MA, Brynildsen MP,

    Metabolic Control of Persister Formation in Escherichia coli, Molecular Cell, 5(4):475-487

    , 2013
  11. Çalık P, Bozkurt B, Zerze GH, İnankur B, Bayraktar E, Boy E, Orman MA, Açık E and Özdamar, TH.,

    Effect of co-substrate sorbitol different feeding strategies on human growth hormone production by recombinant Pichia pastoris. J. Chem. Technol. Biotechnol., 88: 1631–1640

    , 2013
  12. Mattick J, Yang Q, Orman MA, Ierapetritou MG, Berthiaume F, Gale SC, Androulakis IP,

    Impact of Burn Priming on Immune and Metabolic Functions of Whole Liver in a Rat Cecal Ligation and Puncture Model, Intl. J. of Burns and Trauma, 3: 55-65

    , 2013
  13. Orman MA, Brynildsen MP,

    Dormancy is not necessary or sufficient for bacterial persistence, Antimicrobial Agents and Chemotherapy, 57(7): 3230-3239

    , 2013
  14. Orman MA, Brynildsen MP,

    Establishment of a method to rapidly assay bacterial persister metabolism, Antimicrobial Agents and Chemotherapy, 57(9):4398-4409

    , 2013
  15. Orman MA, Ierapetritou MG, Androulakis IP, Berthiaume F,

    Effect of Fasting on the Metabolic Response of Liver to Experimental Burn Injury. PLoS ONE, 8(2): e54825

    , 2013
  16. Mattick J,Yang Q, Orman MA, Ierapetritou MG, Berthiaume F, Androulakis IP,

    Long term gene expression profile dynamics following cecal ligation and puncture in the rat. Journal of Surgical Research, 178: 431-442

    , 2012
  17. Orman MA, Androulakis IP, Berthiaume F, Ierapetritou MG,

    Metabolic Network Analysis of Perfused Livers under Fed and Fasted States: Incorporating Thermodynamic and Futile-Cycle-Associated Regulatory Constraints, Journal of Theoretical Biology, 293:101-110

    , 2012
  18. Orman MA, Ierapetritou MG, Berthiaume F, Androulakis IP,

    Long-term Inflammatory Response of Double-hit Burn and Sepsis Animal Models, Cytokine, 58:307-315

    , 2012
  19. Orman MA, Mattick J, Androulakis IP, Berthiaume F, Ierapetritou MG,

    Stoichiometry Based Steady-State Hepatic Flux Analysis: Computational and Experimental Aspects. Metabolites, 2:268-291

    , 2012
  20. Yang Q, Mattick J, Orman MA, Nyugen TT, Ierapetritou MG, Berthiaume F, Androulakis IP,

    Dynamics of Hepatic Gene Expression Profile in a Rat Cecal Ligation and Puncture Model. Journal of Surgical Research, 176:583-600, (Featured by Global Medical Discovery)

    , 2012
  21. Yang Q, Orman MA, Ierapetritou MG, Berthiaume F, Androulakis IP,

    Dynamics of Short-Term Gene Expression Profiling in Liver following Thermal Injury. Journal of Surgical Research, 176:549-558.

    , 2012
  22. Orman MA, Berthiaume F, Androulakis IP, Ierapetritou MG,

    Advanced Stoichiometric Analysis of Metabolic Networks of Mammalian Cells, Critical Reviews in Biomedical Engineering, 39:511-534

    , 2011
  23. Orman MA, Berthiaume F, Androulakis IP, Ierapetritou MG,

    Pathway analysis of liver metabolism under stressed condition. Journal of Theoretical Biology, 272:131-140.

    , 2011
  24. Orman MA, Ierapetritou MG, Androulakis IP, Berthiaume F,

    Metabolic Response of Perfused Livers to Various Oxygenation Conditions, Biotechnology and Bioengineering, 108:2947-2975

    , 2011
  25. Orman MA, Ierapetritou MG, Berthiaume F, Androulakis IP,

    The Dynamics of the Early Inflammatory Response in Double-hit Burn and Sepsis Animal Models, Cytokine, 56:494-502

    , 2011
  26. Orman MA, Nyugen TT, Ierapetritou MG, Berthiaume F, Androulakis IP,

    Comparison of the Cytokine and Chemokine Dynamics of the Early Inflammatory Response in Models of Burn Injury and Infection, Cytokine, 55:362-371

    , 2011
  27. Orman MA, Arai K, Yarmush ML, Androulakis IP, Berthiaume F, Ierapetritou MG,

    Metabolic Flux Determination in Perfused Livers by Mass Balance Analysis: Effect of Fasting. Biotechnology and Bioengineering, 107:825-835

    , 2010
  28. Orman MA, Calik P, Ozdamar TH,

    The influence of carbon sources on recombinant-human-growth hormone production by Pichia pastoris is dependent on phenotype: a comparison of Mut(s) and Mut(+) strains. Biotechnology and Applied Biochemistry, 52:245-255

    , 2009
  29. Calik P, Orman MA, Celik E, Halloran M, Calik G, Ozdamar TH,

    Expression system for synthesis and purification of recombinant human growth hormone in Pichia pastoris and structural analysis by MALDIToF mass spectrometry. Biotechnology Progress, 24:221-226

    , 2008